Ensures effective Biofilm destruction function, without tissue toxicity
Bacterial Log reduction in Biofilm CFU/mL after 1h of treatment
Bacterial Strain | Saline | SilverStream |
Pseudomonas aeruginosa | 1.59 | 4.84 |
Staphylococcus aureus (MRSA) | 1.66 | 5.44 |
SilverStream has proven to destroy Biofilms
SilverStream® Antimicrobial Mechanism of Action
Ag NO3 | Preservative & Anti-microbial agent | Ionic silver kills on contact and inhibits the growth of bacteria, yeast, and fungi |
Menthol | Penetration enhancer Growth promoter Pain reliever Odor fighter | Enhances ionic silver antimicrobial activities and fights wound odor Promotes granulation tissue growth by vasodilatation |
SilverStream has been tested against many common pathogens and multi-drug-resistant bacterial strains
SilverStream | MIC | MBC | Microbial limits <USP 61> | Zone of inhibition <USP 81> | Antimicrobial preservative <USP 51> |
Escherichia coli | + | + | + | + | + |
Staphylococcus aureus (MRSA) | + | + | + | + | + |
Staphylococcus epidermidis | + | + | ND | ND | ND |
Klebsiella pneumoniae | + | + | ND | ND | ND |
Pseudomonas aeruginosa | ND | ND | + | ND | + |
Candida albicans | ND | ND | ND | ND | + |
Aspergillus niger | ND | ND | ND | ND | + |
Silver Ions induce Apoptosis
Related Case Studies and Publications
References:
1. Evaluation of an Ionic Silver Solution against Dual Species In-Vitro Wound Biofilms: Results of Biofilm Experiments. Center for Biofilm Engineering, Montana USA 2. Use of an Ionic Silver Solution for Wound Cleansing and Reduction in Biomaterial. Thomas E. Serena MD FACS FACHM MAPWCA, St. Vincent Hospital, Erie, PA. USA. 3. Chopra, I: The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern?. J Antimicrobial Chemotherapy 2007; 59: 587-590 4. Dillon, HC: Prevention of gonococcal ophthalmia neonatorium. New Engl J Med 1986; 315: 1414-1415. 5. Evidence for Silver in Wound Care. Joachim Dissemond, Johannes Georg Böttrich, Horst Braunwarth, Jörg Hilt, Patricia Wilken, Karl-Christian, Münter 6. 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd. | JDDG | 1610-0379/2017/1505