SilverStream® products effectively & rapidly clean, moisturize, and soothe Chronic & Hard-To-Treat Wounds. Our safe, free from side effects & effective products are designed to Accelerate Natural Wound Healing Processes.
Our products are based on an innovative combination of a low concentration of silver ions, menthol, glycerol, and a surfactant, dissolved in a hypertonic solution.
The high concentration of the hygroscopic glycerol provides hydrogel effects.
SilverStream® Solution Mechanism of Action
| Ingredient | Action | Description |
|---|---|---|
| Ag NO3 | Preservative & Anti-microbial agent | Ionic silver kills on contact and inhibits the growth of bacteria, yeast, and fungi |
| Menthol | Penetration enhancer Growth promoter Pain reliever Odor fighter | Enhances ionic silver antimicrobial activities and fights wound odor Promotes granulation tissue growth by vasodilatation |
| Tween 20 | Surfactant and Detergent | Enhances solution penetration into the biofilm Acts as wound cleansing detergent |
| Glycerol | A hypertonic aqueous solution that prevents macerations Soothing agent | Aids mechanical removal of exudates and microorganisms Creates Hydrogel function by absorbing water molecules |
| Tris Buffer | Buffered neutral pH | Biocompatible to physiological pH |
SilverStream® Gel Mechanism of Action
| Ingredient | Action | Description |
|---|---|---|
| Ag NO3 | Preservative & Anti-microbial agent | Ionic silver kills on contact and inhibits the growth of bacteria, yeast, and fungi |
| Menthol | Penetration enhancer Growth promoter Pain reliever Odor fighter | Enhances ionic silver antimicrobial activities and fights wound odor Promotes granulation tissue growth by vasodilatation |
| Tween 20 | Surfactant and Detergent | Enhances solution penetration into the biofilm Acts as wound cleansing detergent |
| Glycerol | A hypertonic aqueous solution that prevents macerations Soothing agent | Aids mechanical removal of exudates and microorganisms Creates Hydrogel function by absorbing water molecules |
| Carbopol | Thickening agent | Extends the presence and availability of the product on the wound |
| Tris Buffer | Buffered neutral pH | Biocompatible to physiological pH |
Silver Ions induce Apoptosis
SilverStream proven to destroy Biofilms
Garth James, PhD, Center for Biofilm Engineering, Montana State University-Bozeman, 366 EPS Building, P.O. Box 173980, Bozeman, MT 59717-3980
SilverStream® Solution and SilverStream® Gel Safety
Summary of Biocompatibility Testing Conducted on SilverStream® Solution & SilverStream Gel®
| Biological Effect | Results |
|---|---|
| Irritation | Non-Irritant |
| Acute Systemic Toxicity | Non-Toxic |
| Sensitization | Non-Sensitizing |
| Cytotoxicity Study ISO Direct Contact Method | Non-Cytotoxic |
| Repeated Subcutaneous Toxicity (rats) | Non-Toxic (Gel only) |
| Material-mediated Pyrogenicity (rabbits) | Non-Pyrogenic (Gel only) |
| Assessment of Potential Wound Healing (swine) | Passed (Gel only) |
The Synergy between the SilverStream® Solution and SilverStream® Gel
The synergy provides Extraordinary Wound Healing Results
Recommended synergy treatment in:
- Jet debridement –Jetox De Royal, Versa-Jet (S&N)
- Negative Pressure Wound Treatment- KCI ULTA NPWT, IVT – Vcare & others
